Archimedes Seminar on "Seeing the Invisible - Doing the Impossible: AI-powered diagnosis, treatment and beyond" by Professor Nikos Paragios (University of Paris-Saclay, France, and TheraPanacea, France)

Title: Seeing the Invisible - Doing the Impossible: AI-powered diagnosis, treatment and beyond

Speaker: Professor Nikos Paragios,
(Distinguished Professor of Mathematics, University of Paris-Saclay, France, and Chief Executive and Technical Officer, TheraPanacea, Paris, France)

Abstract: AI is rapidly transforming clinical workflows across healthcare, enabling more precise, quantitative, and personalized cancer care. This talk will present how AI-driven models enhance the entire imaging-to-treatment continuum, from improved image reconstruction and automated tumor segmentation to disease classification, biomarker-based imaging, and “virtual biopsy” approaches that extract biological insights non-invasively. Particular emphasis will be placed on radiotherapy planning and treatment delivery, where generative AI is streamlining contouring, optimizing dose distributions, and accelerating plan generation using generative models. These tools increase accuracy and reproducibility, reduce planning time, and better protect healthy tissues while maintaining tumor control. AI also enables adaptive radiotherapy through rapid re-planning based on anatomical and biological changes during treatment, supporting continuously personalized therapy. Through real-world clinical examples, we will illustrate how these technologies improve efficiency, precision, and outcomes, ultimately paving the way toward data-driven, biomarker-guided, and adaptive cancer treatment.

Short Biography: Nikos Paragios is distinguished professor of Mathematics (on partial leave) at Ecole CentraleSupelec, the school of engineering of the University of Paris-Saclay (#2 in mathematics, #12 in all disciplines according to the Shangai ranking) and Chief Executive Officer of TheraPanacea. Prior to that he was senior fellow (2015-2020) at the Institut Universitaire de France, director (2011-2017) of the Center for Visual Computing at CentraleSupelec, scientific leader (2007-2017) at Inria (Galen Research Team), professor (2004-2005, 2011-2013) at the Ecole de Ponts ParisTech, and affiliated with Siemens Corporate Research (Princeton, NJ, 1999-2004) as a project manager, senior research scientist and research scientist. N. Paragios was an adjunct professor at Rutgers (2002) and at New York University (2004) and a visiting professor at Yale (2007) and at University of Houston (2009). Professor Paragios is a fellow of IEEE (class of 2011), has co-edited four books, published more than 350 papers in the most prestigious journals and conferences (DBLP server), and holds 35 international patents. His work has approximately 35,000 citations according to Google Scholar and his H-number (01/2026) is 80. Professor Paragios has supervised more than 50 PhD students, was the Editor in Chief of the Computer Vision and Image Understanding Journal (CVIU) between 2012 & 2022 and has served in editorial board of numerous and prestigious international journals (IEEE T-PAMI, IJCV, IVC, MVA, JMIV, Medical Image Analysis, SIIMS...). Pr. Paragios received an IBM faculty award in 2014, a European Research Council excellence awards in 2011 & 2016, while in 2008 was the laureate of the Greece's (nationality or descent) highest honor (world-wide) for young academics and scientists, the Bodossaki Prize. In 2006, he was named one of the top 35 innovators world-wide innovators under the age of 35 from the MIT's Technology Review. Professor Paragios is member of the scientific council of Safran conglomerate since 2012 a leading global aerospace, defense, and space technology company with a market capitalization close to €150 billion.

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Supported by:

🔹 Athena Research Center, Greece
🔹 HERON Robotics Center Of Excellence